Sunday, March 9, 2014

Cloning

Celina Mae Revalde
THX 2013-63774
                        Cloning has been one of the most controversial things that science has given the world. But what is cloning? In my own words and understanding, it is basically copying the genes of a person to create another exact same person. It’s like having a twin which looks exactly like you. The perfect replica of you. But, what really is cloning? Cloning is the process of producing similar populations of genetically identical individuals that occurs in nature. Clones are organisms that are exact genetic copies. Every single bit of their DNA is identical.
                         The first ever known clone was the one created from the sheep, Dolly. And that was way back in 1997. We could only imagine how long scientists have been studying about cloning. There are a lot of ways to clone and individual. Actually there are two ways known so far. One is the Artificial Embryo Twinning. It has the same process of creating twins but instead of growing the baby in the mother’s womb, scientists grow them on petri dishes. The embryos develop there for some time. After that, they are then placed inside the surrogate mother where they finish their development. The second process is the SCNT or the Somatic Cell Nuclear Transfer. This uses a different approach than artificial embryo twinning, but it produces the same result: an exact genetic copy, or clone, of an individual. This was the method used to create Dolly the Sheep. Scientists have been conducting experiments in laboratories and sad to say, the process of cloning is not yet that successful.  They have been trying to find ways to improve and widen their knowledge about this. But, these past few years, their hard work had paid off and they are now in great progress and are discovering a lot. As what I have mentioned above, cloning is a very controversial issue. People often ask the question, “Is cloning even ethical? Is it something that we should study further into? Well it actually depends on the way you think. It depends with what you believe in. I have my own opinion about this as a Catholic but since we are not talking about the morality of the act of cloning but the science of it, I am now going to share some recent news about the cloning progress.
                             We all know that stem cell researchers are trying to look for ways to lengthen at least a human’s capacity to live. If not, they are looking for something great that could help the world. Here are some recent news that I have found.
  • ·         Largest ever trial of heart attack patients begins.

Using bone marrow stem cells to prolong life
A total of 3,000 patients will be involved in the trial to test whether life can be prolonged by administering stem cells from the patient's own bone marrow. The stem cells are injected into the patient's heart within 5 days of suffering a heart attack.
  • ·         Reconstructing faces using human stem cells from fat.

Growing cartilage using stem cells taken from the patient's fat
To do this, the doctors would take a small sample of fat from the patient and extract stem cells from it. The stem cells would then be placed onto a special ear-shaped scaffold, called a "POSS-PCU nanoscaffold."

The cells are treated with chemicals that encourage them to transform into cartilage cells, before being inserted under the patient's skin.

This new version of the technique reduces side effects and the chance of the new ear being rejected by the patient's body. It also makes the treatment less invasive, as cartilage taken from the patient's rib to build a scaffold does not grow back.
  • ·         Ability to recreate heart muscle from scar tissue steps closer.

For their study, the team tried turning scarring cells called fibroblasts, obtained from mouse embryos, into heart muscle cells by growing them in gels of varying stiffness.
To begin the conversion of fibroblasts into muscle cells, they infected them with a virus carrying genes expressed by stem cells. These "transgenes" fooled the fibroblasts into behaving like stem cells. Having a tight community of these progenitor cells may have helped with the next step because when they are developing, heart muscle cells are also cosy with their neighbors.
After a week of allowing the cells to develop in the different gels, the researchers added a protein that spurs growth of heart tissue by signaling to the progenitor cells to transform into heart muscle cells.
A few days after this, some of the cell colonies were contracting spontaneously, like colonies of heart muscle cells.

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